Research and Development

Current projects


1.    Production and characterization of biosimilar version of Aflibercept

2.    Production and characterization of cell internalization activities of Tatibody (recombinant Pertuzumab containing the cell penetrating peptide from Tat protein)

3.    Cloning, expression and characterization of an in silico designed variant of interleukin 4, to facilitate its purification using cyanogen bromide

4.    production of human recombinant IL-2 and evaluation of its therapeutic effect in combination with Pertuzumab on an ErbB2 positive breast cancer cell line

5.    Production of a Fc-fused anti-PD-1 scFv and a Fc-fused CD80 for dual blockade of PD-1 and CTLA-4 in cancer immunotherapy.

6.    Real-Time PCR data normalization software design

7.    In silico identification of a cancer associated biomarker and validation in breast cancer patients using Real-Time PCR technique

8.    Designing and evaluating 3rd generation CAR T-meso to induce immune response against pancreatic cancer cell lines



Shiraz University of Medical Sciences
Shiraz Institute for Cancer Research (ICR)
P.O. Box: 71345-3119
Tel: +98(0)71 32303687
Fax: +98(0)71 32304952